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High pressure homogenizer machinery – delivers pressurized mixing

December 30, 2015

homogenizer machinery

High-pressure homogenizer machinery has been the choice machine ever since, when it comes to the disruption of microbial cells. Except highly filamentous and tiny microorganisms, this technique has been discovered as suitable for use in most varieties of yeast, bacteria, and mycelia.

How high pressure homogenizing equipment operates?

This machine forces cell suspensions to go through a narrow orifice or channel using high pressure. Depending on homogenizing tool being used, either the suspension will or will not impinge at top level velocity against other high-velocity cell streams from opposite directions. Machines that have impingement designs are more efficient than those that don’t possess them.

Cell wall disruption is achieved via the combination of pressure drop, focused turbulent eddies, and high impact shearing forces. Cell disruption is actually dependent on the turbulent velocity of the material going into the mixer channel. Such velocity, in turn, is directly in proportion to applied pressure. Hence, if the pressure is high, the disruption efficiency per passing into the machine is high as well.

A number of parameters affect the overall efficiency and operation of high-pressure homogenizer equipment, which are the following; temperature, pressure, valve design, flow rate, impingement design, and number of passes.

More productive than bead mill

High pressured homogenizing machines are the best options when it comes to the need to disrupt microorganisms on a more voluminous scale. In the case of animal tissues, it is also possible for such material to be processed. However, they must be subjected to the actions of a stator rotor blade assembly, paddle mixer, or blade blender.  While the bead mill type has emerged to become a worthy alternative to high pressure mixers, the latter is still the machine to beat when it comes to the capability to process volumes of materials.

To be clear, high pressure homogenizers can process as much as 4,500 liters of materials; while in the case of bead mills, they can only treat around 1,200 liters. Generally, the higher is the pressure, the lesser pass is needed to obtain the desired disruption of cells. It is in this area in which the bead mill has a seeming advantage over high pressure homogenizer; specifically, it involves the number of processing. The latter requires a number of passes to achieve superb disruption, while bead mill type needs materials to pass through the process only once.

French-type high pressure homogenizer

A new type that’s ideal for lab use is the French type. This version utilizes a special piston located within a cylinder to produce high pressures of as much as 40,000 PSI. Since in the French press, heat is generated; the cylinder, piston, and same are pre-cooled. In the case of yeast, pressures needed to disrupt such material range from 8,000 to 9,000 PSI. Likewise, a number of several passes into the press is most likely required to ensure quality of disruption.

As it is, most industries rely on the overall effectiveness of high-pressure homogenizer machinery when it comes to the production of desired emulsions and homogenous materials, since the results from such machines are always able to meet the desired requirements.

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